Therefore, this study assessed whether the same MRSP lineage is present in bitches and their litters in different breeding kennels and is maintained over time. However, data are lacking on the relatedness and transmission of MRSP lineages isolated from bitches and their offspring in breeding kennels. MRSP has also occasionally been isolated from the colostrum and milk of breeding bitches as well as from puppies. Among European isolates, the multi-resistant clonal lineage ST71-J-t02-II–III is dominant, but other emerging clones, such as ST258, have also been detected in some European countries.
MRSP is often regarded as a threat due to limited therapeutic options and because it frequently shows resistance profiles to three or more antimicrobial classes. pseudintermedius (MRSP) detection has rapidly increased in microbiological specimens from pets across Europe in recent years. pseudintermedius as an opportunistic pathogen, it is worrisome that multi-drug methicillin-resistant S. It has been linked to neonatal mortality due to necrotising dermatitis, pododermatitis, acute suppurative interstitial pneumonia, toxaemia and septicaemia.
pseudintermedius is commonly detected in the genital organs of both healthy dogs and dogs with reproductive problems, including in the vaginas of bitches in the pre- and postpartum periods.
#B1 archiver pup skin
Staphylococcus pseudintermedius belongs to the bacterial skin flora of canines and is a common opportunistic pathogen of dogs. MRSP colonization did not affect the health conditions of the bitches or of their litters. Our data show that MRSP circulation can differ in different settings, that several clonal lineages can circulate together, and that vertical transmission appears common. MRSP was only isolated from litters of MRSP-positive bitches, thus suggesting that bitch-litter transmission is likely. In addition, most isolates from both kennels had multi-resistant antibiotic profiles. In kennel B, only a new isolate, ST772, was detected. In kennel A, circulating strains were from 7-locus sequence types ST688, ST258 and closely related isolates of ST71, which included most isolates. The analysis revealed different situations in both investigated kennels.
The study was carried out from October 2014 to March 2016 and included successive parturitions from the same animals. Post-partum bitches (at day 3 vaginal and day 3, 9 and 35 milk samples) and their litters (at day 3, 9 and 35 oral and abdominal skin samples) from two Italian breeding kennels (A and B) were sampled and MRSP was subsequently characterized via whole-genome sequencing and antibiotic susceptibility testing. This study assessed whether MRSP lineage differs between breeding kennels and is maintained over time. MRSP has also been isolated from bitches and newborns in dog breeding kennels. Multi-drug methicillin-resistant Staphylococcus pseudintermedius (MRSP) detection is rapidly increasing in microbial specimens from pets across Europe.
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